PROXIMATE, MINERAL COMPOSITION AND PHYTO-CONSTITUENTS OF SOME MEDICINAL PLANTS/HERBS IN INDIA
Keywords:
Medicinal plants, Phytochemicals, Toxicity, Treatment, Antimicrobial, ResistanceAbstract
This study was conducted to assess the proximate, mineral content, and phyto-constituents of several therapeutic plants and herbs found in India. The medicinal properties of herbs are attributable to the existence of several complex chemical substances known as secondary metabolites, which are exclusively accumulated in diverse sections of the plant such as leaves, stems, roots, and flowers. These secondary metabolites or phytochemicals contain saponins, alkaloids, flavonoids, triterpenoids, diterpenoids, tannins, and steroids, which are considered a valuable source of nutrition and also possess pharmacological properties such as antimicrobial, anfungal, antiviral, antihelminthic, antioxidant, hepato-protective, antibacterial, immunostimulatory, hypolipidemic, anti-rheumatic, antidiarrheal, anti-pyretic, antimalarial, anticancer, and anti-allergic properties, among others. Medicinal plant extracts have traditionally been used to treat diseases and inhibit the activities of pathogenic organisms such as Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Enterococcus faecalis, Staphylococcus aureus, Bacillus subtilis, Penicillium notatum, and Candida albicans. It was determined that all medicinal plants investigated had varied chemical compositions, which might be ascribed to the plant's age, specie, extraction procedure or processing, storage, geographical location, and other factors. This study will also provide information on emerging phyto-constituents, which can help to lower the growing incidence of antimicrobial resistance and bridge the gap between animal production and food safety.References
[1] Singh N, Singh JP, Singh V. Effect of dietary supplementation of herbal formulation on dressing percentage and mortality in broiler chicks. Indian J. Vet., 2002, 2: 22-24.
[2] Wojcikowski, K, Johnson, DW, Gobé, G. Medicinal herbal extracts -- renal friend or foe? Part one: the toxicities of medicinal herbs. Nephrology, 2004, 9(5): 313-318.
[3] Phillipson, JD. Assays for antimalarial and amoebicidal activities. In: Methods in plant biochemistry, ed. Hostettmann K., Academic Press Limited, Great Yarmouth. Norfol, 1991, 135-152.
[4] Smolinski, MS, Hamburg, MA, Lederberg, J. (eds). Microbial threats to health: Emergence, detection, and response. Washington, DC: Institute of Medicine, National Academies Press, 2003, 203-210.
[5] Tzortzakis, NG, Economakis, CD. Antifungal activity of lemongrass (Cympopogon citratus L.) essential oil against key postharvest pathogens. Innovative Food Science Emerging Technology, 2007, 8: 253-258.
[6] Voravuthikunchai, SP, Kitpipit, L. Activities of crude extracts of Thai medicinal plants on methicillin- resistant Staphylococcus aureus. Journal of Clinical Microbiology and Infection, 2003, 9: 236.
[7] Zhang, Y, Liu, X, Wang, Y, et al. Antibacterial Activity and Mechanism of Cinnamon Essential Oil Against Escherichia Coli and Staphylococcus Aureus. Food Control, 2016, 59, 282-289. DOI: 10.1016/j.foodcont.2015.05.032.
[8] Winkel-Shirley, B. Update on flavonoid biosynthesis: Flavonoid Biosynthesis. A Colorful Model for Genetics, Biochemistry, Cell Biology, and Biotechnology. Plant Physiology, 2001, 126(2): 485- 493.
[9] Yadav, J, Arya, V, Yadav, S, et al. Cassia Occidentalis L.: A Review on its Ethnobotany, Phytochemical and Pharmacological Profile. Fitoterapia, 2010, 81(4): 223-230.
[10] Valgas, C, Souza, SMd, Smania, EF, et al. Screening Methods to Determine Antibacterial Activity of Natural Products. Brazilian Journal of Microbiology, 2007, 38(2): 369-380.
[11] World Health Organization, (WHO). Promoting the Role of Traditional Medicine in Health Systems: A Strategy for the African Region 2001-2010. Harare, World Health Organization, 2000, 10- 286.
[12] Daniel Nnadozie Anorue, Friday Ubong, Alagbe Olujimi John. Investigating the effects of pawpaw (Carica papaya) essential oil dietary supplementation on the growth performance and carcass characteristics of broilers. Agricultural and Veterinary Sciences, 2023, 7(3): 164-174.
[13] Musa, B, Alagbe, JO, Adegbite Motunrade Betty, et al. Growth performance, caeca microbial population and immune response of broiler chicks fed aqueous extract of Balanites aegyptiaca and Alchornea cordifolia stem bark mixture. United Journal for Research and Technology, 2020, 2(2):13-21.
[14] Demain, AL, Fang, A. The Natural Functions of Secondary Metabolites. History of Modern Biotechnology I. ed. by Anon: Springer, 2000, 69, 1-39. DOI: https://doi.org/10.1007/3-540-44964-7_1.
[15] Daglia, M. Polyphenols as Antimicrobial Agents'. Current Opinion in Biotechnology, 2012, 23(2): 174-181.
[16] Ayanwuyi, LO, Yaro, AH, Abodunde, OM. Analgesic and Anti-Inflammatory Effects of the Methanol Stem Bark Extract of Prosopis Africana. Pharmaceutical Biology, 2010, 48(3): 296-299.
[17] Trentin, DD, Giordani, RB, Zimmer, KR, et al. Potential of Medicinal Plants from the Brazilian Semi-Arid Region (Caatinga) Against Staphylococcus Epidermidis Planktonic and Biofilm Lifestyles. Journal of Ethnopharmacology, 2011, 137(1): 327-335.
[18] Yasunaka, K, Abe, F, Nagayama, A, et al. Antibacterial Activity of Crude Extracts from Mexican Medicinal Plants and Purified Coumarins and Xanthones. Journal of Ethnopharmacology, 2005, 97(2): 293-299.
[19] Alagbe, JO, Shittu, MD, Ushie, FT. GC-MS analysis of methanolic stem bark extract of Zollingeriana indigofera. Asian Journal of Advances in Research, 2021, 11(4): 144-146.
[20] Tolari S, Rudroju S, Penchala S, et al. Quantification of total phenolics and Total Flavonoid contents in extracts of Oroxylum Indicum I. Kurz. Asain Journal of Pharmaceutical and Clinical Research, 2012, 5(4): 177-179.
[21] Makkar HPS, Norsambuu T, Lkhavatsere, S, et al. Plant Secondary metabolites in some medical plants of Mongolia used for enhancing animal health and production. Tropicultura, 2009, 27 (3): 159-167.
[22] Alagbe, JO. Growth performance and haemato-biochemical parameters of broilers fed different levels of Parkia biglobosa leaf extracts. Academic Journal of Life Sciences, 2019, 5(12): 107-115.
[23] Alagbe, JO, Sadiq, MR, Anaso, EU, et al. Efficacy of Albizia lebbeck seed oil on the growth performance and carcass characteristics of weaner rabbits. Sumerianz Journal of Agriculture and Veterinary, 2019, 2(12): 116-122.
[24] González-Lamothe, R, Mitchell, G, Gattuso, M, et al. (2009) 'Plant Antimicrobial Agents and their Effects on Plant and Human Pathogens'. International Journal of Molecular Sciences, 2009, 10(8): 3400-3419.
[25] Andrew, F, Olugbenga, OD, Oluwakamisi, FA. Assessment of Nutritonal and Antioxidant properties of Dysphania ambrosiodes and Crassocephalum crepidiodes leaf meal as potential feed additives. Turkish Journal of Agriculture Food Science and Technology, 2022, 11(2): 274-279.
[26] Alagbe, JO, Muritala, SD, Aduragbemi, YA, et al. The approximate mineral and phytochemical content of the leaves, stem bark and roots of Pterocapus erinaceus in India. Cerrado: Agricultural and Biological Research, 2024, 1(1): 32-41.
[27] Mohammad, A, Lurwan, M, Sani, U, et al. Determination of proximate, phytochemicals and mineral composition of Verononia amygdalina leaves. Nutraceutical Research, 2020, 1(1): 1-7.
[28] Ojediran, TK, Emiola, IA, Duroja