PERSPECTIVE OF BASAL CELL CARCINOMA : A REVIEW
Volume 3, Issue 1, Pp 7-10, 2025
DOI: https://doi.org/10.61784/wjcs3016
Author(s)
Olaleye Wasiu Babatunde1*, Nnodim Johnkennedy2
Affiliation(s)
1Department of Public Health, Louisiana State University Shreveport, Louisiana, USA.
2Department of Medical Laboratory Science, Imo State University, Owerri, Nigeria.
Corresponding Author
Olaleye Wasiu Babatunde
ABSTRACT
The most common cause of Basal Cell Carcinoma (BCC) is DNA damage brought on by exposure to ultraviolet (UV) radiation from the sun or indoor tanning, which alters the basal cells of the epidermis, the skin's outermost layer and causes unchecked growth.Open sores, red patches, pink growths, shiny bumps, scars, or growths with a central indentation and/or slightly elevated, rolled edges are all possible appearances for BCCs. At times, BCCs may ooze, crust, itch or bleed. Usually, the lesions appear in parts of the body that are exposed to the sun.About half of BCCs in patients with darker skin are pigmented, which means they are tan, black, or brown in color and could be confused with a typical mole. It's crucial to remember that various people may have very varied BCCs.
KEYWORDS
Basal cell carcinoma; Perspective; A review
CITE THIS PAPER
Olaleye Wasiu Babatunde, Nnodim Johnkennedy. Perspective of basal cell carcinoma: a review. World Journal of Clinical Sciences. 2025, 3(1): 7-10. DOI: https://doi.org/10.61784/wjcs3016.
REFERENCES
[1] Mendenhall WM, Amdur RJ, Hinerman RW, et al. Radiotherapy for cutaneous squamous and basal cell carcinomas of the head and neck. Laryngoscope, 2009, 119(10): 1994-9.
[2] Erba P, Farhadi J, Wettstein R, et al. Morphoeic basal cell carcinoma of the face. Scand J Plast Reconstr Surg Hand Surg, 2007, 41(4): 184-8.
[3] Keyhani K, Ashenhurst M, Oryschak. A. Periocular basal cell carcinoma arising in a site of previous trauma. Can J Ophthalmol, 2007, 42(3): 467-8.
[4] Collins L, Quinn A, Stasko T. Skin Cancer and Immunosuppression. Dermatol Clin, 2017, 37(1): 83-94.
[5] Zhang Y, Cartmel B, Choy CC, et al. Body mass index, height and early-onset basal cell carcinoma in a case-control study. Cancer Epidemiol, 2017, 46: 66-72.
[6] Patel MS, Thigpen JT, Vance RB, et al. Basal cell carcinoma with lung metastasis diagnosed by fine-needle aspiration biopsy. South Med J, 1999, 92(3): 321-4.
[7] Akinci M, Aslan S, Markoc F, et al. Metastatic basal cell carcinoma. Acta Chir Belg, 2008, 108(2): 269-72.
[8] Mc Loone NM, Tolland J, Walsh M. Follow-up of basal cell carcinomas: an audit of current practice. J Eur Acad Dermatol Venereol, 2006, 20(6): 698-701.
[9] Kim DP, Kus KJB, Ruiz E. Basal Cell Carcinoma Review. Hematol Oncol Clin North Am, 2019, 33(1): 13-24.
[10] Loh TY, Rubin AG, Brian Jiang SI. Basal Cell Carcinoma of the Dorsal Hand: An Update and Comprehensive Review of the Literature. Dermatol Surg, 2016, 42(4): 464-70.
[11] Ozyazgan I, Kontas O. Previous injuries or scars as risk factors for the development of basal cell carcinoma. Scand J Plast Reconstr Surg Hand Surg, 2004, 38(1): 11-5.
[12] Jia HX, He YL. Efficacy and safety of imiquimod 5% cream for basal cell carcinoma: a meta-analysis of randomized controlled trial. J Dermatolog Treat, 2020, 31(8): 831-838.
[13] Mohanty P, Mohanty L, Devi BP. Multiple cutaneous malignancies in xeroderma pigmentosum. Indian J Dermatol Venereol Leprol, 2001, 67(2): 96-7
[14] Keyhani K, Ashenhurst M, Oryschak A. Periocular basal cell carcinoma arising in a site of previous trauma. Can J Ophthalmol, 2007, 42(3): 467-8.
[15] Ferrucci LM, Cartmel B, Molinaro AM, et al. Indoor tanning and risk of early-onset basal cell carcinoma. J Am Acad Dermatol, 2012, 67(4): 552-62.
[16] Karagas MR. Occurrence of cutaneous basal cell and squamous cell malignancies among those with a prior history of skin cancer. The Skin Cancer Prevention Study Group. J Invest Dermatol, 1994, 102(6): 10S-13S.
[17] Nasr I. British Association of Dermatologists’ Clinical Standards Unit. British Association of Dermatologists guidelines for the management of adults with basal cell carcinoma 2021. Br J Dermatol, 2021, 185(5): 899-920.
[18] Kauvar AN, Cronin T Jr, Roenigk R, et al. American Society for Dermatologic Surgery. Consensus for nonmelanoma skin cancer treatment: basal cell carcinoma, including a cost analysis of treatment methods. Dermatol Surg, 2015, 41(5): 550-71.
[19] Micali M, Nasca MR, Musumeci ML. Treatment of an extensive superficial basal cell carcinoma of the face with imiquimod 5% cream. Int J Tissue React, 2005, 27(3): 111-4.