Author(s)

Xin Chen^# , Ping Yang^# , Juan Zhou, Wenpin Lo, Xiao-Min Xiao^*

Affiliation(s)

Department of Obstetrics and Gynecology, the First Affiliated Hospital of Jinan University, Guangzhou, 510630, China.

Corresponding Author

Xiao-Min Xiao

ABSTRACT

Aims: To analyse the shape of time-blood glucose curve during oral glucose (OGTT) tolerance test in pregnant women, and providing reference for future tracing scheme of blood glucose monitoring postpartum for women with a history of gestational diabetes mellitus (GDM). Methods: From January 2012 to September 2015, Pregnant women who have regular antenatal examination in the first affiliated hospital of JINAN university were selected as subjects (N=12390 cases). The OGTT was carried out during 24 to 28 weeks and the results were analysed retrospectively. Results: (1) The detection rate of GDM and PGDM were 21.63% and 1.24% respectively. (2) The majority of subjects in the GDM group was those with impaired glucose tolerance (IGT) (66.92%), followed by normal glucose tolerance (NGT) (31.02%). (3) In the GDM-IGT subgroup, the percentage of subject with type B curve was the largest (74.2%). In the GDM-NGT subgroup, the percentage of subject with type III curve was the largest (93.2%). (4) The majority of subjects in the NGDM group was those with impaired glucose tolerance (IGT) (11.18%). In the GDM-IGT subgroup, the percentage of subject with type B curve was the largest (66.82%). Conclusions: In summary, for women with a history of GDM, not all the people (about 25.82%) have high risk of development of type 2 diabetes. However, in women without a history of GDM, about 66.82% of the population still needs to be vigilant in order to prevent type 2 diabetes in the future.

KEYWORDS

Pregnancy; High blood glucose; Oral glucose tolerance test; Curve shape; Insulin metabolism

CITE THIS PAPER

Xin Chen, Ping Yang, Juan Zhou, Wenpin Lo, Xiao-Min Xiao. The analyzation of time-blood glucose curve during oral glucose tolerance test in pregnant women. Acta Translational Medicine. 2018, 1(2): 10-14.

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