Author(s)

Safavi Alireza

Affiliation(s)

Tehran University of Medical Sciences, Tehran, Iran.

Corresponding Author

Safavi Alireza

ABSTRACT

Helicobacter pylori infection is the main cause of gastric cancer, peptic ulcer, chronic gastritis, gastric mucosa-associated lymphoid tissue lymphoma and other diseases, and is related to some extra-gastrointestinal diseases such as iron deficiency anemia. Eradication therapy is the only effective way to cure Helicobacter pylori-related diseases, but the increase in drug resistance makes it increasingly difficult to eradicate Helicobacter pylori with chemical drugs and antibiotics. Finding active ingredients that inhibit and kill Helicobacter pylori from traditional medicine is an effective way to develop new Helicobacter pylori treatment drugs. This article reviews the current status of the application of traditional Chinese medicine, Tibetan medicine, Mongolian medicine, Yao medicine, Zhuang medicine and other traditional Chinese medicine methods in the treatment of Helicobacter pylori infection.

KEYWORDS

Traditional medicine; Helicobacter pylori; Alternative therapy

CITE THIS PAPER

Safavi Alireza. Progress in the investigation of traditional medicine’s therapeutic effects on helicobacter pylori infection. Journal of Pharmaceutical and Medical Research. 2024, 6(2): 1-5. DOI: 10.61784/jpmrv6n216.

REFERENCES

[1]Poddar U. Helicobacter pylori: a perspective in low-and middle-income countries. Paediatrics and international child health, 2019, 39(1): 13-17.

[2]Talebi Bezmin Abadi A. Diagnosis of Helicobacter pylori Using Invasive and Noninvasive Approaches. Journal of pathogens, 2018.

[3]Crowe SE. Helicobacter pylori Infection. The New Eng- land journal of medicine, 2019, 380(12): 1158-1165.

[4]Safavi M, Shams-Ardakani M, Foroumadi A. Medicinal plants in the treatment of Helicobacter pylori infections. Pharmaceutical biology, 2015, 53(7): 939-960.

[5]Salehi B, Sharopov F, Martorell M. Phytochemicals in Helicobacter pylori infections: What are we doing now?. International Journal of Molecular Sciences, 2018, 29(8): 2361-2394.

[6] Hu Fulian, Zhang Shengsheng. National consensus on integrated traditional Chinese and Western medicine in the treatment of Helicobacter pylori-related “diseases and syndromes”. Journal of Gastroenterology and Hepatology, 2018, 27(9): 1008-1006.

[7] Pawar R, Patil U, Gadekar R. A potential of some medicinal plants as an antiulcer agents. Pharmacognosy Reviews, 2020, 4(8): 136.

[8] Ayala G, Escobedo-Hinojosa WI, Cruz-Herrera CFDL. Exploring alternative treatments for Helicobacter pylori infection. World Journal of Gastroenterology Wjg, 2014 (6): 1450-1469.

[9] Hu Yingjun. Modernization of traditional Chinese medicine. Chinese Health Nutrition, 2019, 29(23): 382.

[10] Wang Xulin, Jiao Wenling, Lu Zongshun. Preliminary screening of traditional Chinese medicines for inhibiting Helicobacter pylori. Chinese Journal of Integrated Traditional Chinese and Western Medicine, 1994, 14(9): 534-536.

[11] Wang Hengqi, Li Yang, Guo Anjun. Study on the in vitro anti-Helicobacter pylori activity of 10 kinds of Chinese herbal medicine extracts. Medical Information, 2013, 26 (9): 155-156.

[12] Xu Yi, Ye Bai, Shan Zhaowei. Study on the inhibitory effect of single and compound Chinese herbal medicine on Helicobacter pylori. Chinese Journal of Integrated Traditional Chinese and Western Medicine Spleen and Stomach, 2000, 8 (5): 292-293.

[13] Zhang Jinyan, Guo Xiujuan, Zheng Jinxiu. Study on the in vitro antibacterial activity of Chinese medicine Coptis chinensis and Huangfen against four kinds of bacteria. Chinese Journal of Medical Laboratory Medicine, 2007, 5 (6): 544-546.

[14]Si XB, Zhang XM, Lan Y. Berberine-based quadruple therapy for patients with Helicobacter pylori associated peptic ulcer: a meta-analysis. World Chinese Journal of Digestology, 2018, 26(32): 1864-1873.

[15] Yang Xingtang. Research on anti-Helicobacter pylori components of licorice monomers. Wuhan: Tongji University, 2007.

[16] Lu Enji, Li Tie. Clinical observation on 80 cases of Helicobacter pylori-related gastric ulcer treated with modified Gancao Xiexin Decoction. Harbin Medicine, 2018, 38(6): 570-571.

[17] Gu Shengqing, Lin Liang. Clinical study of Gancao Xiexin decoction combined with quadruple therapy in the treatment of Helicobacter pylori-related gastric ulcer. China Rural Health, 2017, 14 (8): 43-44.

[18] David Lian, Yifei Xu, Wenkang Ren. Patchouli alcohol inhibits the activity of Helicobacter pylori adenase and its mechanism. Chinese Journal of Traditional Chinese Medicine, 2017, 42(3): 562-566.

[19] Zhang Xiaolin, Wu Yanxiang, Lu Fan. Research on the anti-Helicobacter pylori effect of bitter melon aqueous extract and its extraction process. Food and Machinery, 2016, 32(8): 136-139.

[20] Yang Hongsheng. Clinical study on Sihuang Tiaowei Decoction combined with PPI triple therapy in the treatment of Helicobacter pylori-related gastritis and peptic ulcer. Asia Pacific Traditional Medicine, 2017, 13(14): 124-125.

[21] Liu Xiaoming. The efficacy of Banxia Xiexin Decoction in the treatment of duodenal ulcer infected by Helicobacter pylori and its impact on IL-6 levels. Journal of Clinical Medical Literature, 2018, 5(12): 148-149.

[22] Xu Ying. Analysis of the efficacy of Jinghua Weikang capsules combined with triple therapy in the treatment of chronic gastritis caused by Helicobacter pylori infection in the elderly. Journal of Clinical Medical Literature, 2018, 3(63): 163.

[23] Jimuse, Gan Qiulan, Li Qianrong. The development history of Tibetan medicine, national characteristics and future prospects. Asia-Pacific Traditional Medicine, 2019, 15(7): 50-52.

[24] Hua Erjiang. Observation on the clinical efficacy of Tibetan medicine in the treatment of Helicobacter pylori infection. Chinese Journal of Ethnic Medicine, 2015.

[25] Suo Jinlan. 100 cases of Helicobacter pylori-related peptic ulcer treated with Tibetan medicine. Chinese Modern Distance Education of Traditional Chinese Medicine, 2008, 6 (4): 367-368.

[26] Guan Baozhu, Bai Yuhua, Jie Xiao. Briefly describe the characteristics of Mongolian medicine in treating diseases. Chinese Journal of Ethnic Medicine, 2017, 23(9): 57-59.

[27] Wang Wuyue, Huricha Bater. Clinical observation of Mongolian medicine in the treatment of Helicobacter pylori infectious gastric disease. World Latest Medical Information Abstracts, 2016, 16(65): 151,400.

[28] Hu Wenhua, Jin Tao. Clinical efficacy of Mongolian medicine combined with quadruple therapy in the treatment of chronic gastritis with Helicobacter pylori infection. Chinese Journal of Ethnic Medicine, 2019, 25(5): 3-5.

[29] Su Yilatu. Analysis of the clinical efficacy of Mongolian medicine Bater-7 Pills in the treatment of gastric Helicobacter pylori. Chinese Health Nutrition, 2015, 30 (12): 75.

[30] Lu Qiaoxia. Professor Li Tong’s discussion on medical ethics. 2016 National Medical Development Summit Forum, 2016: 264-269.

[31] Liu Xiaomei, Li Haiqiang. Observation on the efficacy of shaking medicine jar combined with quadruple therapy in the treatment of Helicobacter pylori-related gastritis (spleen and stomach damp-heat type). Asia Pacific Traditional Medicine, 2017, 13(19): 12-14.

[32] Shao Jiemei, Deng Hui. Clinical study on the treatment of peptic ulcer with Zhuangyao Yuyang Powder. Chinese Journal of Ethnic Medicine, 2014, 20(7): 1-2.

[33] Zhang Huang, Wang Yanfeng, Wang Jiangtao. Screening study on fifty kinds of commonly used aphrodisiacs in Guangxi against Helicobacter pylori infection. Journal of Jiangxi University of Traditional Chinese Medicine, 2009, 21 (5): 66-68.

[34] Wu Weihua, Cao Chunya, Xiao Congying. Preliminary study on the anti-gastric ulcer action mechanism of the aqueous extract of Xue Ma Bu (Guangdong purple pearl); proceedings of the Sixth National (2015) National Symposium on Serum Medicine. Proceedings of the Medical Theory Training Conference, Liping, Guizhou, F, 2015.

[35] Zhang Xihe, Liang Zhengpei, Wu Guangxin. Clinical observation on drug treatment of duodenal ulcer. Chinese Journal of Ethnic Medicine, 2007, 13(11): 7.