Author(s)

TianYao Liu

Affiliation(s)

Harbin Blood Center, Harbin 150056, Heilongjiang, China.

Corresponding Author

TianYao Liu

ABSTRACT

Objective To understand the situation of occult hepatitis B virus infection among voluntary blood donors in Harbin City, analyze its epidemiological characteristics, and assess the risk of transfusion-transmitted hepatitis B virus infection. Methods The results of hepatitis B surface antigen (HBsAg) ELISA double reagent negative and hepatitis B virus nucleic acid (HBV DNA) positive tests from 1,020,943 voluntary blood donors at the Harbin Blood Center from January 2016 to December 2022 were analyzed. Statistical analysis was performed on the total positive rate of occult HBV infection among voluntary blood donors, in relation to gender and whether it was their first time donating blood. Results Among the 1,020,943 voluntary blood donors at the Harbin Blood Center from January 2016 to December 2022, the overall positive rate of HBV infection was 0.032%, with little difference between genders, which was not statistically significant. However, there was a difference between first-time and repeat donors, which was statistically significant (P＜0.05). Conclusion The positive rate of HBV among voluntary blood donors in the Harbin area is related to whether they are repeat donors. Therefore, it is necessary to strengthen the promotion of knowledge about voluntary blood donation and infectious diseases, to avoid high-risk behaviors. It is important to scientifically compile recruitment guidelines and conduct health consultations before blood donation. Developing a low-risk group of voluntary blood donors can reduce transfusion risks and improve blood safety quality.

KEYWORDS

HBV DNA nucleic acid testing (NAT); Blood screening; Occult hepatitis B virus infection (OBI); Transfusion risk

CITE THIS PAPER

TianYao Liu. Investigation of occult hepatitis B virus infection among voluntary blood donors in Harbin area. Journal of Pharmaceutical and Medical Research. 2024, 6(2): 35-40. DOI: 10.61784/jpmr3005.

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